full transcript
From the Ted Talk "Cynthia Kenyon: Experiments that hint of longer lives"

Unscramble the Blue Letters

Well it turns out that in the daf-2 mutants, a whole lot of genes are switched on in the DNA that encode proteins that protect the cells and the tissues, and eiaprr damage. And the way that they're switched on is by a gene regulator protein called FOXO. So in a daf-2 nmttau — you see that I have the X rwnad here through the receptor. The ereocrtp isn't working as well. Under those conditions, the FOXO protein in blue has gone into the nucleus — that little compartment there in the middle of the cell — and it's sitting down on a gene binding to it. You see one gene. There are lots of segne actually that bind on xoof. And it's just sitting on one of them.

Open Cloze

Well it turns out that in the daf-2 mutants, a whole lot of genes are switched on in the DNA that encode proteins that protect the cells and the tissues, and ______ damage. And the way that they're switched on is by a gene regulator protein called FOXO. So in a daf-2 ______ — you see that I have the X _____ here through the receptor. The ________ isn't working as well. Under those conditions, the FOXO protein in blue has gone into the nucleus — that little compartment there in the middle of the cell — and it's sitting down on a gene binding to it. You see one gene. There are lots of _____ actually that bind on ____. And it's just sitting on one of them.

Solution

  1. repair
  2. mutant
  3. foxo
  4. genes
  5. receptor
  6. drawn

Original Text

Well it turns out that in the daf-2 mutants, a whole lot of genes are switched on in the DNA that encode proteins that protect the cells and the tissues, and repair damage. And the way that they're switched on is by a gene regulator protein called FOXO. So in a daf-2 mutant — you see that I have the X drawn here through the receptor. The receptor isn't working as well. Under those conditions, the FOXO protein in blue has gone into the nucleus — that little compartment there in the middle of the cell — and it's sitting down on a gene binding to it. You see one gene. There are lots of genes actually that bind on FOXO. And it's just sitting on one of them.

ngrams of length 2

collocation frequency
long time 5
long lived 5
live longer 5
hormone receptor 5
normal worms 3
normal worm 3
foxo genes 3
age related 3

Important Words

  1. bind
  2. binding
  3. blue
  4. called
  5. cell
  6. cells
  7. compartment
  8. conditions
  9. damage
  10. dna
  11. drawn
  12. encode
  13. foxo
  14. gene
  15. genes
  16. lot
  17. lots
  18. middle
  19. mutant
  20. mutants
  21. nucleus
  22. protect
  23. protein
  24. proteins
  25. receptor
  26. regulator
  27. repair
  28. sitting
  29. switched
  30. tissues
  31. turns
  32. working