full transcript
"From the Ted Talk by Samuel Cohen: Alzheimer's is not normal aging — and we can cure it"

Unscramble the Blue Letters

Remember Dr. Alzheimer found strange puaeqls and tangles in Auguste's brain a century ago. For almost a century, we didn't know much about these. Today we know they're made from protein mloleuces. You can imagine a protein molecule as a piece of paper that normally folds into an elaborate piece of oigmrai. There are spots on the paper that are sticky. And when it folds cetclrroy, these sticky bits end up on the inside. But sometimes things go wrong, and some sticky bits are on the outside. This causes the protein molecules to stick to each other, forming clumps that eaunllvtey become large plaques and tangles. That's what we see in the birans of Alzheimer's patients.

Open Cloze

Remember Dr. Alzheimer found strange _______ and tangles in Auguste's brain a century ago. For almost a century, we didn't know much about these. Today we know they're made from protein _________. You can imagine a protein molecule as a piece of paper that normally folds into an elaborate piece of _______. There are spots on the paper that are sticky. And when it folds _________, these sticky bits end up on the inside. But sometimes things go wrong, and some sticky bits are on the outside. This causes the protein molecules to stick to each other, forming clumps that __________ become large plaques and tangles. That's what we see in the ______ of Alzheimer's patients.

Solution

  1. eventually
  2. molecules
  3. brains
  4. correctly
  5. origami
  6. plaques

Original Text

Remember Dr. Alzheimer found strange plaques and tangles in Auguste's brain a century ago. For almost a century, we didn't know much about these. Today we know they're made from protein molecules. You can imagine a protein molecule as a piece of paper that normally folds into an elaborate piece of origami. There are spots on the paper that are sticky. And when it folds correctly, these sticky bits end up on the inside. But sometimes things go wrong, and some sticky bits are on the outside. This causes the protein molecules to stick to each other, forming clumps that eventually become large plaques and tangles. That's what we see in the brains of Alzheimer's patients.

ngrams of length 2

collocation frequency
protein molecules 3

Important Words

  1. alzheimer
  2. bits
  3. brain
  4. brains
  5. century
  6. clumps
  7. correctly
  8. dr
  9. elaborate
  10. eventually
  11. folds
  12. forming
  13. imagine
  14. large
  15. molecule
  16. molecules
  17. origami
  18. paper
  19. patients
  20. piece
  21. plaques
  22. protein
  23. remember
  24. spots
  25. stick
  26. sticky
  27. strange
  28. tangles
  29. today
  30. wrong