full transcript

From the Ted Talk by Geraldine Hamilton: Body parts on a chip

Unscramble the Blue Letters

Organs on chips could also change the way we do caclniil trials in the future. Right now, the average participant in a clinical trial is that: average. Tends to be mdilde aged, tends to be female. You won't find many clinical trials in which children are involved, yet every day, we give children medications, and the only safety data we have on that drug is one that we obtained from adults. Children are not adults. They may not respond in the same way adults do. There are other things like genetic differences in populations that may lead to at-risk populations that are at risk of having an adverse drug rtecioan. Now imagine if we could take cells from all those different populations, put them on ciphs, and cretae populations on a chip. This could really change the way we do clinical trials. And this is the team and the people that are doing this. We have engineers, we have cell biologists, we have clinicians, all working together. We're really seeing something quite indrelbice at the Wyss ittsutnie. It's really a convergence of dsinpliices, where biology is icfiennnulg the way we design, the way we engineer, the way we bluid. It's pretty exciting.

Open Cloze

Organs on chips could also change the way we do ________ trials in the future. Right now, the average participant in a clinical trial is that: average. Tends to be ______ aged, tends to be female. You won't find many clinical trials in which children are involved, yet every day, we give children medications, and the only safety data we have on that drug is one that we obtained from adults. Children are not adults. They may not respond in the same way adults do. There are other things like genetic differences in populations that may lead to at-risk populations that are at risk of having an adverse drug ________. Now imagine if we could take cells from all those different populations, put them on _____, and ______ populations on a chip. This could really change the way we do clinical trials. And this is the team and the people that are doing this. We have engineers, we have cell biologists, we have clinicians, all working together. We're really seeing something quite __________ at the Wyss _________. It's really a convergence of ___________, where biology is ___________ the way we design, the way we engineer, the way we _____. It's pretty exciting.

Solution

  1. chips
  2. reaction
  3. disciplines
  4. influencing
  5. institute
  6. middle
  7. clinical
  8. create
  9. build
  10. incredible

Original Text

Organs on chips could also change the way we do clinical trials in the future. Right now, the average participant in a clinical trial is that: average. Tends to be middle aged, tends to be female. You won't find many clinical trials in which children are involved, yet every day, we give children medications, and the only safety data we have on that drug is one that we obtained from adults. Children are not adults. They may not respond in the same way adults do. There are other things like genetic differences in populations that may lead to at-risk populations that are at risk of having an adverse drug reaction. Now imagine if we could take cells from all those different populations, put them on chips, and create populations on a chip. This could really change the way we do clinical trials. And this is the team and the people that are doing this. We have engineers, we have cell biologists, we have clinicians, all working together. We're really seeing something quite incredible at the Wyss Institute. It's really a convergence of disciplines, where biology is influencing the way we design, the way we engineer, the way we build. It's pretty exciting.

Frequently Occurring Word Combinations

ngrams of length 2

collocation frequency
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cells experience 3
mechanical forces 3
blood cells 3
clinical trials 3
animal testing 2
dynamic environments 2
human lung 2
add human 2
human cells 2
blood channel 2
pretty exciting 2
organ chips 2
adverse drug 2
stem cells 2

ngrams of length 3

collocation frequency
white blood cells 3

Important Words

  1. adults
  2. adverse
  3. aged
  4. average
  5. biologists
  6. biology
  7. build
  8. cell
  9. cells
  10. change
  11. children
  12. chip
  13. chips
  14. clinical
  15. clinicians
  16. convergence
  17. create
  18. data
  19. day
  20. design
  21. differences
  22. disciplines
  23. drug
  24. engineer
  25. engineers
  26. exciting
  27. female
  28. find
  29. future
  30. genetic
  31. give
  32. imagine
  33. incredible
  34. influencing
  35. institute
  36. involved
  37. lead
  38. medications
  39. middle
  40. obtained
  41. organs
  42. participant
  43. people
  44. populations
  45. pretty
  46. put
  47. reaction
  48. respond
  49. risk
  50. safety
  51. team
  52. trial
  53. trials
  54. working
  55. wyss