full transcript

From the Ted Talk by Melissa J. Moore: How mRNA medicine will change the world

Unscramble the Blue Letters

Now, you may think of protein as simply something that you need to eat, an important part of your diet, something that's important for you to build mcusle. But it's not just muscle that contains protein. pteiorn makes up a huge fraction of the incredibly complicated ecosystem that's your eitrne body. In many ways, your body fcntuions like a large city, full of myriad buildings, icreotencnetnd buildings, with lots of different structures. Now, just as the word "building" fials to capture the incredible variety of structures that make up any large city, the geinrec term "protein" gives no clue as to the incredible variety of molecular architectures at the molecular lveel. Like buildings, proteins are not monolithic. Our body makes many proteins. Some, like the collagen in our skin that makes our skin tough but pliable. Like the actin and myosin in our muscles that enable us to move. Or our boold is full of hemoglobin, ferrying oxgeyn around. anitideobs protecting us from disease, and clotting factors that clsoe up our wounds. And for any of you that have ever cracked a biochemistry textbook, this should look familiar. This is the metabolic chart of the human body. These are all of the reactions in your body that are kiepeng you alive and well right now. And each one of those reactions is catalyzed by a different protein whose names are swohn here in blue. So proteins are not only what makes up the bulk of your body, they’re also what make your body tick and keep you well.

Open Cloze

Now, you may think of protein as simply something that you need to eat, an important part of your diet, something that's important for you to build ______. But it's not just muscle that contains protein. _______ makes up a huge fraction of the incredibly complicated ecosystem that's your ______ body. In many ways, your body _________ like a large city, full of myriad buildings, ______________ buildings, with lots of different structures. Now, just as the word "building" _____ to capture the incredible variety of structures that make up any large city, the _______ term "protein" gives no clue as to the incredible variety of molecular architectures at the molecular _____. Like buildings, proteins are not monolithic. Our body makes many proteins. Some, like the collagen in our skin that makes our skin tough but pliable. Like the actin and myosin in our muscles that enable us to move. Or our _____ is full of hemoglobin, ferrying ______ around. __________ protecting us from disease, and clotting factors that _____ up our wounds. And for any of you that have ever cracked a biochemistry textbook, this should look familiar. This is the metabolic chart of the human body. These are all of the reactions in your body that are _______ you alive and well right now. And each one of those reactions is catalyzed by a different protein whose names are _____ here in blue. So proteins are not only what makes up the bulk of your body, they’re also what make your body tick and keep you well.

Solution

  1. shown
  2. level
  3. functions
  4. fails
  5. interconnected
  6. blood
  7. muscle
  8. antibodies
  9. oxygen
  10. entire
  11. protein
  12. close
  13. keeping
  14. generic

Original Text

Now, you may think of protein as simply something that you need to eat, an important part of your diet, something that's important for you to build muscle. But it's not just muscle that contains protein. Protein makes up a huge fraction of the incredibly complicated ecosystem that's your entire body. In many ways, your body functions like a large city, full of myriad buildings, interconnected buildings, with lots of different structures. Now, just as the word "building" fails to capture the incredible variety of structures that make up any large city, the generic term "protein" gives no clue as to the incredible variety of molecular architectures at the molecular level. Like buildings, proteins are not monolithic. Our body makes many proteins. Some, like the collagen in our skin that makes our skin tough but pliable. Like the actin and myosin in our muscles that enable us to move. Or our blood is full of hemoglobin, ferrying oxygen around. Antibodies protecting us from disease, and clotting factors that close up our wounds. And for any of you that have ever cracked a biochemistry textbook, this should look familiar. This is the metabolic chart of the human body. These are all of the reactions in your body that are keeping you alive and well right now. And each one of those reactions is catalyzed by a different protein whose names are shown here in blue. So proteins are not only what makes up the bulk of your body, they’re also what make your body tick and keep you well.

Frequently Occurring Word Combinations

ngrams of length 2

collocation frequency
messenger rna 10
messenger rnas 10
building blocks 5
personalized cancer 5
clinical trials 4
cancer vaccines 4
human body 3
mrna medicines 3
incredible variety 2
metabolic chart 2
building materials 2
trillion cells 2
protein molecules 2
inborn metabolic 2
metabolic errors 2
recruiting patients 2
clinical trial 2
manufacturing equipment 2
mrna sequence 2
tumor cells 2
rna vaccines 2

ngrams of length 3

collocation frequency
personalized cancer vaccines 4
inborn metabolic errors 2
messenger rna vaccines 2

Important Words

  1. actin
  2. alive
  3. antibodies
  4. architectures
  5. biochemistry
  6. blood
  7. blue
  8. body
  9. build
  10. buildings
  11. bulk
  12. capture
  13. catalyzed
  14. chart
  15. city
  16. close
  17. clotting
  18. clue
  19. collagen
  20. complicated
  21. cracked
  22. diet
  23. disease
  24. eat
  25. ecosystem
  26. enable
  27. entire
  28. factors
  29. fails
  30. familiar
  31. ferrying
  32. fraction
  33. full
  34. functions
  35. generic
  36. hemoglobin
  37. huge
  38. human
  39. important
  40. incredible
  41. incredibly
  42. interconnected
  43. keeping
  44. large
  45. level
  46. lots
  47. metabolic
  48. molecular
  49. monolithic
  50. move
  51. muscle
  52. muscles
  53. myosin
  54. myriad
  55. names
  56. oxygen
  57. part
  58. pliable
  59. protecting
  60. protein
  61. proteins
  62. reactions
  63. shown
  64. simply
  65. skin
  66. structures
  67. term
  68. textbook
  69. tick
  70. tough
  71. variety
  72. ways
  73. word
  74. wounds