full transcript

From the Ted Talk by Jennifer Pluznick: You smell with your body, not just your nose

Unscramble the Blue Letters

In my lab, we work on trying to understand the roles of oclfortay receptors and ttase receptors in the context of the kidney. The kidney is a cntaerl control center for homeostasis. And to us, it makes ssene that a homeostatic control center would be a logical place to employ chemical sensors. We've identified a nubemr of different olfactory and taste receptors in the kidney, one of which, olfactory rpceetor 78, is known to be expressed in cells and tissues that are important in the regulation of blood puesrsre. When this receptor is deleted in mice, their blood pressure is low. Surprisingly, this receptor was found to respond to chemicals called short-chain fatty acids that are produced by the bacteria that reside in your gut — your gut microbiota. After being produced by your gut microbiota, these chemicals are absorbed into your bloodstream where they can then interact with rpeoertcs like olfactory receptor 78, maneing that the changes in meibtoslam of your gut microbiota may influence your blood pressure.

Open Cloze

In my lab, we work on trying to understand the roles of _________ receptors and _____ receptors in the context of the kidney. The kidney is a _______ control center for homeostasis. And to us, it makes _____ that a homeostatic control center would be a logical place to employ chemical sensors. We've identified a ______ of different olfactory and taste receptors in the kidney, one of which, olfactory ________ 78, is known to be expressed in cells and tissues that are important in the regulation of blood ________. When this receptor is deleted in mice, their blood pressure is low. Surprisingly, this receptor was found to respond to chemicals called short-chain fatty acids that are produced by the bacteria that reside in your gut — your gut microbiota. After being produced by your gut microbiota, these chemicals are absorbed into your bloodstream where they can then interact with _________ like olfactory receptor 78, _______ that the changes in __________ of your gut microbiota may influence your blood pressure.

Solution

  1. receptor
  2. taste
  3. pressure
  4. olfactory
  5. sense
  6. receptors
  7. central
  8. metabolism
  9. number
  10. meaning

Original Text

In my lab, we work on trying to understand the roles of olfactory receptors and taste receptors in the context of the kidney. The kidney is a central control center for homeostasis. And to us, it makes sense that a homeostatic control center would be a logical place to employ chemical sensors. We've identified a number of different olfactory and taste receptors in the kidney, one of which, olfactory receptor 78, is known to be expressed in cells and tissues that are important in the regulation of blood pressure. When this receptor is deleted in mice, their blood pressure is low. Surprisingly, this receptor was found to respond to chemicals called short-chain fatty acids that are produced by the bacteria that reside in your gut — your gut microbiota. After being produced by your gut microbiota, these chemicals are absorbed into your bloodstream where they can then interact with receptors like olfactory receptor 78, meaning that the changes in metabolism of your gut microbiota may influence your blood pressure.

Frequently Occurring Word Combinations

ngrams of length 2

collocation frequency
olfactory receptors 9
olfactory receptor 5
taste receptors 4
chemical sensors 3
blood pressure 3
blood vessels 2
sensitive chemical 2
control center 2
gut microbiota 2

ngrams of length 3

collocation frequency
sensitive chemical sensors 2

Important Words

  1. absorbed
  2. acids
  3. bacteria
  4. blood
  5. bloodstream
  6. called
  7. cells
  8. center
  9. central
  10. chemical
  11. chemicals
  12. context
  13. control
  14. deleted
  15. employ
  16. expressed
  17. fatty
  18. gut
  19. homeostasis
  20. homeostatic
  21. identified
  22. important
  23. influence
  24. interact
  25. kidney
  26. lab
  27. logical
  28. meaning
  29. metabolism
  30. mice
  31. microbiota
  32. number
  33. olfactory
  34. place
  35. pressure
  36. produced
  37. receptor
  38. receptors
  39. regulation
  40. reside
  41. respond
  42. roles
  43. sense
  44. sensors
  45. surprisingly
  46. taste
  47. tissues
  48. understand
  49. work