full transcript
"From the Ted Talk by David Anderson: Your brain is more than a bag of chemicals"

Unscramble the Blue Letters

Remarkably, we find we can completely dissociate these two abnormalities. If we put a good copy of the dopamine receptor back in this elliptical structure called the central complex, the flies are no longer hyperactive, but they still can't learn. On the other hand, if we put the receptor back in a different structure cealld the mushroom body, the learning diiceft is rcseeud, the flies learn well, but they're still hyperactive. What that tells us is that dopamine is not bathing the brain of these flies like soup. Rather, it's acting to control two different functions on two different circuits, so the reason there are two things wrong with our dopamine roeecptr feils is that the same receptor is controlling two different functions in two different rnogeis of the bairn. Whether the same thing is true in ADHD in humans we don't know, but these kinds of ruelsts should at least cause us to consider that possibility.

Open Cloze

Remarkably, we find we can completely dissociate these two abnormalities. If we put a good copy of the dopamine receptor back in this elliptical structure called the central complex, the flies are no longer hyperactive, but they still can't learn. On the other hand, if we put the receptor back in a different structure ______ the mushroom body, the learning _______ is _______, the flies learn well, but they're still hyperactive. What that tells us is that dopamine is not bathing the brain of these flies like soup. Rather, it's acting to control two different functions on two different circuits, so the reason there are two things wrong with our dopamine ________ _____ is that the same receptor is controlling two different functions in two different _______ of the _____. Whether the same thing is true in ADHD in humans we don't know, but these kinds of _______ should at least cause us to consider that possibility.

Solution

  1. receptor
  2. brain
  3. regions
  4. rescued
  5. deficit
  6. results
  7. flies
  8. called

Original Text

Remarkably, we find we can completely dissociate these two abnormalities. If we put a good copy of the dopamine receptor back in this elliptical structure called the central complex, the flies are no longer hyperactive, but they still can't learn. On the other hand, if we put the receptor back in a different structure called the mushroom body, the learning deficit is rescued, the flies learn well, but they're still hyperactive. What that tells us is that dopamine is not bathing the brain of these flies like soup. Rather, it's acting to control two different functions on two different circuits, so the reason there are two things wrong with our dopamine receptor flies is that the same receptor is controlling two different functions in two different regions of the brain. Whether the same thing is true in ADHD in humans we don't know, but these kinds of results should at least cause us to consider that possibility.

ngrams of length 2

collocation frequency
dopamine receptor 10
psychiatric disorders 8
fruit flies 7
air puffs 5
specific neurons 3
mutant flies 3
receptor mutant 3
side effects 3
chemical soup 3
learning disabilities 3

ngrams of length 3

collocation frequency
dopamine receptor mutant 3
receptor mutant flies 3

ngrams of length 4

collocation frequency
dopamine receptor mutant flies 3

Important Words

  1. abnormalities
  2. acting
  3. adhd
  4. bathing
  5. body
  6. brain
  7. called
  8. central
  9. circuits
  10. completely
  11. complex
  12. control
  13. controlling
  14. copy
  15. deficit
  16. dissociate
  17. dopamine
  18. elliptical
  19. find
  20. flies
  21. functions
  22. good
  23. hand
  24. humans
  25. hyperactive
  26. kinds
  27. learn
  28. learning
  29. longer
  30. mushroom
  31. possibility
  32. put
  33. reason
  34. receptor
  35. regions
  36. remarkably
  37. rescued
  38. results
  39. soup
  40. structure
  41. tells
  42. true
  43. wrong